Document Type
Article
Publication Date
10-2002
Source Publication
Mechanisms of Development
Abstract
Sexual reproduction in the ciliate Tetrahymena follows a complex developmental program involving the sequential regulation of dozens of genes. Genes that are up-regulated during post-zygotic development in Tetrahymena were isolated by subtractive hybridization. Anlagen stage induced gene 1 (ASI1) encodes a 2.8 kb transcript that contains a single intron and is induced during macronuclear development. ASI1 is a single copy gene in both the micronucleus and the macronucleus. It encodes a 95 kDa conceptual protein with a leucine zipper near the amino terminus
Comments
Originally published in Mechanisms of Development, Volume 118, No. 1-2 (October 2002), online at: http://dx.doi.org/10.1016/S0925-4773(02)00259-9