Title

Nuclear Dualism

Document Type

Contribution to Book

Language

eng

Format of Original

24 cm, 24 p.

Publication Date

2012

Publisher

Elsevier

Source Publication

Methods in Cell Biology, Vol. 109

Source ISSN

9780123859679

Abstract

Nuclear dualism is a characteristic feature of the ciliated protozoa. Tetrahymena have two different nuclei in each cell. The larger, polyploid, somatic macronucleus (MAC) is the site of transcriptional activity in the vegetatively growing cell. The smaller, diploid micronucleus (MIC) is transcriptionally inactive in vegetative cells, but is transcriptionally active in mating cells and responsible for the genetic continuity during sexual reproduction. Although the MICs and MACs develop from mitotic products of a common progenitor and reside in a common cytoplasm, they are different from one another in almost every respect.

Comments

"Nuclear Dualism," in Methods in Cell Biology, Vol. 109. Ed. Kathleen Collins. Philadelphia: Elsevier, 2012: 29-52. DOI.