Title

Survey of Neuropeptide-like Immunoreactivity in the Lamprey Spinal Cord

Document Type

Article

Language

eng

Format of Original

4 p.

Publication Date

4-7-1987

Publisher

Elsevier

Source Publication

Brain Research

Source ISSN

0006-8993

Abstract

The distribution of neural elements immunoreactive to several peptides with a possible messenger role was studied in the lamprey spinal cord by using an indirect immunofluorescence method. Different patterns of immunoreactive (IR) fibers were detected by antisera raised against cholecystokinin, metorphamide, bombesin, galanin, corticotropin-releasing factor, somatostatin, peptide YY, neurotensin, calcitonin and FMRFamide. Somatostatin-IR cell bodies were located around the central canal. All immunoreactivity could be abolished by preabsorption with the corresponding peptide. The results suggest that the lamprey spinal cord has several fiber systems containing peptides sharing immunogenic properties with mammalian neuropeptides.

Comments

Brain Research, Vol. 408, No. 1-2 (April 7, 1987): 299-302. DOI.

James Buchanan was affiliated with the Karolinska Institute at the time of publication.