Pigeon Breeder's Disease. Antibody Response of Man Against a Purified Component of Pigeon Dropping Extract
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Clinical Immunology and Immunopathology
A homogeneous component of pigeon dropping extract, one of the etiologic agents of pigeon breeder's disease (PBD), was used to evaluate some of the antibody responses using serum from patients with PBD. Their responses were compared with those of similarly exposed, but asymptomatic, pigeon breeders. As assessed by antigen-binding capacity, quantitative precipitation, and complement fixation, the responses from these two groups were qualitatively similar. In general, these results are in agreement with other studies using pigeon serum components. Since symptomatic and asymptomatic pigeon breeders are not readily discriminated by results of tests for humoral immunity, we suggest that other factors are important in the pathogenesis of PBD.