Title

RNA Turnover: Unexpected Consequences of Being Tailed

Document Type

Article

Language

eng

Format of Original

4 p.

Publication Date

8-23-2005

Publisher

Elsevier

Source Publication

Current Biology

Source ISSN

0960-9822

Abstract

In eukaryotic cells, the 3′ poly(A) tails found on mRNA influence their stability and translation. The discovery of a second nuclear poly(A) polymerase complex has fueled a series of reports defining a new and unexpected role for 3′ end poly(A) tails in the nuclear surveillance and turnover of noncoding RNAs and intergenic mRNAs of unknown function.

Comments

Current Biology, Vol. 15, No. 16 (August 23, 2005): R635-R638. DOI.