Document Type

Article

Language

eng

Format of Original

3 p.

Publication Date

1979

Publisher

Georg Thieme Verlag

Source Publication

Hormone and Metabolic Research

Source ISSN

0018-5043

Original Item ID

doi: 10.1055/s-0028-1092729; Shelves: QP 801 .H7 H65 Mem Lvl Lower

Abstract

Cytochrome oxidase, glycerol-3-phosphate dehydrogenase, and succinate dehydrogenase were measured in mitochondrial fractions obtained from rat soleus muscle of control and 8 week T3 + T4 treated animals. Under these conditions of prolonged treatment, there is a five-fold increase in the specific activities of both cytochrome oxidase and glycerols-3-phosphate dehydrogenase. Significant increases in total cellular mitochondrial content and enzyme activities were observed in T3 + T4 treated animals as compared to controls. These results indicate that thyrotoxicosis can induce selective changes in mitochondrial enzymes in slow twitch red (Type I) muscle fibers.

Comments

Published version. Hormone and Metabolic Research, Vol. 11, No. 4 (1979): 304-306. DOI. © Georg Thieme Verlag (an imprint of Thieme Publishing) 1979. Used with permission.

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