Title

The Latest Lessons Learned from Retrieval Analyses of Ultra-High Molecular Weight Polyethylene, Metal-on-Metal, and Alternative Bearing Total Disc Replacements

Document Type

Article

Language

eng

Format of Original

4 p.

Publication Date

3-2012

Publisher

Elsevier

Source Publication

Seminars in Spine Surgery

Source ISSN

1040-7383

Original Item ID

doi: 10.1053/j.semss.2011.11.011

Abstract

Knowledge regarding the in vivo performance and periprosthetic tissue response of cervical and lumbar total disc replacements (TDRs) continues to expand. This review addresses the following 4 main questions: (1) What are the latest lessons learned from using polyethylene in large joints and how are they relevant to current TDRs? (2) What are the latest lessons learned regarding adverse local tissue reactions from metal-on-metal cobalt-chrome bearings in large joints and how are they relevant to current TDRs? (3) What advancements have been made in understanding the in vivo performance of alternative biomaterials, such as stainless steel and polycarbonate urethane, for TDRs in the past 5 years? (4) How has retrieval analysis of all these various artificial disc bearing technologies advanced the state-of-the-art in preclinical testing of TDRs? The study of explanted artificial discs and their associated tissues can help inform bearing selection as well as the design of future generations of disc arthroplasty. Analyzing retrieved artificial discs is also essential for validating preclinical test methods.

Comments

Seminars in Spine Surgery, Vol. 24, No. 1 (March 2012): 57-70. DOI.