Title

Recent Applications of the Simple Hydrocarbon Cyclooctatetrene as a Starting Material for Complex Molecule Synthesis

Document Type

Article

Publication Date

2012

Source Publication

Mini-Reviews in Organic Chemistry

Abstract

Cyclooctatetraene [COT], a simple non-aromatic cyclic polyene, is capable of undergoing a variety of oxidation and cycloaddition reactions to afford polycyclic structures. In addition, complexation of COT or the cycloaddition products with transition metals facilitates bond formation. Recent developments in the reactivity of COT and application to the synthesis of naturally occurring and non-naturally occurring compounds is reviewed.

Comments

Mini-Reviews in Organic Chemistry, Volume 9, Number 1, pp 31-43 (February 2012). DOI: 10.2174/157019312799079983