Title

Synthesis of N-Succinyl-L,L-Diaminopimelic Acid Mimetics Via Selective Protection

Document Type

Article

Publication Date

2010

Source Publication

Protein & Peptide Letters

Source ISSN

0929-8665

Abstract

The search for potential inhibitors that target so far unexplored bacterial enzyme mono-N-succinyl-L,Ldiaminopimelic acid desuccinylase (DapE) has stimulated a development of methodology for quick and efficient preparation of mono-N-acylated 2,6-diaminopimelic acid (DAP) derivatives bearing the different carboxyl groups or lipophilic moieties on their amino group.

Comments

Protein & Peptide Letters. Vol. 17, No. 3 (2010): 405-409. DOI.

Richard C. Holz was affiliated with Loyola University-Chicago at the time of publication.