Title

Chelate-Assisted Oxidative Coupling Reaction of Arylamides and Unactivated Alkenes: Mechanistic Evidence for Vinyl C–H Bond Activation Promoted by an Electrophilic Ruthenium-Hydride Catalyst

Document Type

Article

Publication Date

10-21-2010

Source Publication

Organometallics

Source ISSN

0276-7333

Abstract

The cationic ruthenium hydride complex [(η6-C6H6)(PCy3)(CO)RuH]+BF4 was found to be a highly regioselective catalyst for the oxidative C−H coupling reaction of aryl-substituted amides and unactivated alkenes to give o-alkenylamide products. The kinetic and spectroscopic analyses support a mechanism involving a rapid vinyl C−H activation followed by a rate-limiting C−C bond formation step.

Comments

Organometallics, Vol. 29, No. 22 (October 21, 2010): 5748-5750. DOI.