Title

Efficient Dehydrogenation of Amines and Carbonyl Compounds Catalyzed by a Tetranuclear Ruthenium-μ-oxo-μ-hydroxo-hydride Complex

Document Type

Article

Publication Date

2009

Source Publication

Organometallics

Source ISSN

0276-7333

Abstract

The tetranuclear ruthenium-μ-oxo-μ-hydroxo-hydride complex {[(PCy3)(CO)RuH]44-O)(μ3-OH)(μ2-OH)} (1) was found to be a highly effective catalyst for the transfer dehydrogenation of amines and carbonyl compounds. For example, the initial turnover rate of the dehydrogenation of 2-methylindoline was measured to be 1.9 s−1 with a TON of 7950 after 1 h at 200 °C. The extensive H/D scrambling patterns observed from the dehydrogenation reaction of indoline-N-d1 and indoline-α-d2 suggest a monohydride mechanistic pathway with the C−H bond activation rate-limiting step.

Comments

Organometallics, Vol. 28, No. 4 (February 23, 2009): 947-949. DOI.