De novo synthesis of polyhydroxyl aminocyclohexanes

Authors

Anobick Sar, Marquette University
Sergey Lindeman, Marquette UniversityFollow
William Donaldson, Marquette UniversityFollow

Document Type

Article

Publication Date

7-2010

Publisher

Royal Society of Chemistry

Source Publication

Organic and Biomolecular Chemistry

Source ISSN

1477-0520

Abstract

The syntheses of 12 stereochemically diverse polyhydroxyl aminocyclohexane (“aminocyclitols”) derivatives are described. These short syntheses require 2–5 steps from N-(2,4-cyclohexadien-1-yl)phthalimide, which is prepared in two steps from tricarbonyl(cyclohexadienyl)iron(1+). The relative stereochemistries of the aminocyclitols were assigned by ¹H NMR spectroscopy as well as X-ray diffraction analysis.

Comments

Accepted version. Organic and Biomolecular Chemistry, 8 (2010), DOI: 10.1039/C004730A. © 2010 Royal Society of Chemistry. Used with permission.

Recommended Citation

Sar, Anobick; Lindeman, Sergey; and Donaldson, William, "De novo synthesis of polyhydroxyl aminocyclohexanes" (2010). Chemistry Faculty Research and Publications. 42.
https://epublications.marquette.edu/chem_fac/42