Title
De novo synthesis of polyhydroxyl aminocyclohexanes
Document Type
Article
Publication Date
7-2010
Source Publication
Organic and Biomolecular Chemistry
Abstract
The syntheses of 12 stereochemically diverse polyhydroxyl aminocyclohexane (“aminocyclitols”) derivatives are described. These short syntheses require 2–5 steps from N-(2,4-cyclohexadien-1-yl)phthalimide, which is prepared in two steps from tricarbonyl(cyclohexadienyl)iron(1+). The relative stereochemistries of the aminocyclitols were assigned by 1H NMR spectroscopy as well as X-ray diffraction analysis.
supplemental_OBC8-2010.pdf (886 kB)
Supplemental materials
Supplemental materials
Comments
Organic and Biomolecular Chemistry, 8 (2010), DOI: 10.1039/C004730A