Title

Chemoselective Formation of Unsymmetrically Substituted Ethers from Catalytic Reductive Coupling of Aldehydes and Ketones with Alcohols in Aqueous Solution

Document Type

Article

Language

eng

Format of Original

4 p.

Publication Date

2015

Publisher

American Chemical Society

Source Publication

Organic Letters

Source ISSN

1523-7060

Original Item ID

DOI: 10.1021/acs.orglett.5b00553

Abstract

A well-defined cationic Ru–H complex catalyzes reductive etherification of aldehydes and ketones with alcohols. The catalytic method employs environmentally benign water as the solvent and cheaply available molecular hydrogen as the reducing agent to afford unsymmetrical ethers in a highly chemoselective manner.

Comments

Organic Letters, Vol. 17, No. 7 (2015): 1778-1781. DOI.