Development of Organoiron Methodology for the C8-C16 Dienylamine Segment of the Streptogramin Antibiotics

Authors

Fahim Ahmed, Marquette UniversityFollow
Yeyu Cao, Marquette UniversityFollow
William Donaldson, Marquette UniversityFollow

Document Type

Article

Publication Date

5-2005

Source Publication

Letters in Organic Chemistry

Abstract

Methodology for preparation of the C8-C16 dienylamine segment of the streptogramin antibiotics is based on a diastereoselective nitrile oxide-olefin cycloaddition to a (triene)iron complex. The Fe(CO)3 adjunct also serves as a protecting group for the subsequent reductive hydrolysis of the isoxazoline ring.

Comments

Letters in Organic Chemistry, Vol. 2, No. 3 (May 2005) pp 222-225. DOI: 10.2174/1570178053765366

Recommended Citation

Ahmed, Fahim; Cao, Yeyu; and Donaldson, William, "Development of Organoiron Methodology for the C8-C16 Dienylamine Segment of the Streptogramin Antibiotics" (2005). Chemistry Faculty Research and Publications. 57.
https://epublications.marquette.edu/chem_fac/57