A short synthesis of the common dihydropyran segment of the antifungal agents ambruticin and jerangolid A

Authors

Julie Lukesh, Marquette UniversityFollow
William Donaldson, Marquette UniversityFollow

Document Type

Article

Publication Date

8-2005

Publisher

Elsevier

Source Publication

Tetrahedron Letters

Source ISSN

0040-4039

Abstract

The dihydropyranyl segment common to ambruticin and jerangolid A was prepared in six steps (31.7% yield) from (S)-2-benzyloxypropanal via silyloxydiene cyclocondensation, followed by C-glycosidation, and eventual epimerization at C18.

Comments

Accepted version. Tetrahedron Letters, Vol. 46, No. 33 (August 2005) pp. 5529-5531. DOI: 10.1016/j.tetlet.2005.06.040. © 2005 Elsevier. Used with permission.

Recommended Citation

Lukesh, Julie and Donaldson, William, "A short synthesis of the common dihydropyran segment of the antifungal agents ambruticin and jerangolid A" (2005). Chemistry Faculty Research and Publications. 58.
https://epublications.marquette.edu/chem_fac/58