Title

Recent Applications of Acyclic (Diene)iron Complexes and (Dienyl)iron Cations in Organic Synthesis

Grant Title

Natural Products Synthesis via Organoiron Methodology

Document Type

Article

Publication Date

8-2009

Source Publication

European Journal of Organic Chemistry

Source ISSN

1434-193X

Abstract

Complexation of (tricarbonyl)iron to an acyclic diene serves to protect the ligand against oxidation, reduction, and cycloaddition reactions, whereas the steric bulk of this adjunct serves to direct the approaches of reagents to unsaturated groups attached to the diene onto the face opposite to iron. Furthermore, the Fe(CO)3 moiety can serve to stabilize carbocation centers adjacent to the diene (i.e. pentadienyl-iron cations). Recent applications of these reactivities to the synthesis of polyene-, cyclopropane-, cycloheptadiene-, and cyclohexenone-containing natural products or analogues are presented.

Document Rights and Citation of Original

Accepted version. European Journal of Organic Chemistry, Volume 2009, Issue 23 (August 2009). pp 3831-3843. DOI: 10.1002/ejoc.200900141 © Wiley-VCH Verlag 2009. Used with permission.

This is the pre-peer reviewed version of the article, which has been published in final form.