Document Type

Conference Proceeding

Language

eng

Format of Original

12 p.

Publication Date

2010

Publisher

Society of Photo-optical Instrumentation Engineers

Source Publication

Proceedings of SPIE Medical Imaging 2010

Abstract

This work optimized a multi-pinhole collimator for a stationary three-camera Single Photon Emission Computed Tomography (SPECT) system designed for rapid (one-second) dynamic imaging through simulations. Multi-pinhole collimator designs were investigated to increase efficiency and angular sampling while maintaining adequate spatial resolution for small-animal imaging. The study first analytically investigated the tradeoffs between efficiency and spatial resolution as a function of the number of pinholes. An oval arrangement of pinholes was proposed, and the benefits compared to a circular arrangement were quantified through simulations. Finally, collimators with six to nine pinholes were simulated, and the resulting data compared with respect to efficiency, signal-to-noise ratio (SNR), and the angular coverage in Radon space. All simulations used the GATE Monte Carlo toolkit. The results suggest that an oval arrangement of nine pinholes improved the efficiency and SNR by factors of 1.65 and 1.3, respectively, compared to a circular arrangement. A nine-pinhole collimator was found to provide the highest geometric efficiency (~6.35*104cps/mCi) and improved the SNR by a factor of ~1.3 and ~1.1 compared to the six- and eight-pinhole collimators, respectively. Overall, the simulated multi-pinhole system depicted cylindrical objects despite the limited angular sampling and scan time of the one-second, stationary three-camera acquisition.

Comments

SPIE Medical Imaging 2010: 1-12. DOI. © Society of Photo-Optical Instrumentation Engineers 2010. Used with permission.

Copyright 2010 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

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