Title

Interleukin-1 Receptor Antagonist Polymorphism and Birth Timing: Pathway Analysis Among African American Women

Document Type

Article

Language

English

Publication Date

3-2017

Publisher

Lippincott Williams & Wilkins, Inc

Source Publication

Nursing Research

Source ISSN

ISSN: 0029-6562

Abstract

Timing of birth is a major determinant of newborn health. African American women are at increased risk for early birth, particularly via the inflammatory pathway. Variants of the IL1RN gene, which encode the interleukin-1 receptor antagonist (IL-1Ra) protein, are implicated in early birth. The biological pathways linking these variables remain unclear. Evidence also suggests that inflammatory pathways differ by race; however, studies among African American women are lacking.

Comments

Nursing Research, Vol. 66, No. 2 (March/April 2017): 954-104. DOI