Document Type

Article

Language

eng

Publication Date

4-2021

Publisher

Elsevier

Source Publication

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology

Source ISSN

2212-4403

Abstract

Objective

Temporomandibular disorder (TMD) is a multifactorial condition and the most common cause of orofacial pain, affecting mostly women, which points to a female hormone predilection. Therefore, the aim of this study was to analyze the association between TMD and estrogen receptor alpha 1 expression in disks of patients with TMD and condyle fracture (CFx).

Study Design

Forty specimens (from 27 patients) included n = 8 CFx, n = 21 anterior disk displacement with reduction (ADDwR), and n = 11 anterior disk displacement without reduction (ADDwoR). Age, area, and intensity of immunostaining were statistically compared between CFx, ADDwR, and ADDwoR groups using analysis of variance and Kruskal-Wallis analysis (P < .05).

Results

No significant difference between CFx, ADDwR, and ADDwoR groups with respect to age and expression of estrogen receptor alpha 1 was observed on immunohistochemical examination.

Conclusion

No association of estrogen receptor alpha 1 expression and age was found in the CFx, ADDwR, and ADDwoR groups.

Comments

Accepted version. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 131, No. 4 (April 2021): e89-e94. DOI. © 2021 Elsevier. Used with permission.

Available for download on Monday, November 01, 2021

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