Antibody Production by Non-Immune Rat Spleen Cells Incubated with RNA from Spleens of Rats Immunized with Sheep Red Blood Cells or Bovine Serum Albumin

Danute S. Juras, Marquette University


Quantitative and qualitative studies of the immune response occuring [sic] in various species of animals exposed to different types of antigens have revealed that antibody formation is preceded by differentiation and proliferation of lymphoid cells (1-4). The mechanism by which an antigen induces such a complex series of events is basic to an understanding of antibody synthesis.