Format of Original
PM & R
Original Item ID
doi: 10.1016/j.pmrj.2011.02.014; PubMed Central: PMCID 3328806
To determine if folic acid supplementation improves vascular function (brachial artery flow-mediated dilation [FMD]) in professional dancers with known endothelial dysfunction.
Prospective cross-sectional study.
Academic institution in the Midwestern United States.
Twenty-two professional ballet dancers volunteered for this study.
Main Outcome Measures
Subjects completed a 3-day food record to determine caloric and micronutrient intake. Menstrual status was determined by interview and questionnaire. Endothelial function was determined as flow-induced vasodilation measured by high-frequency ultrasound of the brachial artery. A change in brachial diameter of
Sixty-four percent of dancers (n = 14) had abnormal brachial artery FMD (P< .0001).
This study reveals that vascular endothelial function improves in dancers after supplementation with folic acid (10 mg/day) for at least 4 weeks. This finding may have clinically important implications for future cardiovascular disease risk prevention.