Vaginal and Rectal Microbiome Changes Following Administration of a Multi-Species Antenatal Probiotic: A Randomized Control Trial

Authors

Emily Malloy, Marquette UniversityFollow
Ashley Kates, National Library of Medicine
Jonah Dixon, University of Wisconsin-Madison
Colleen Riley, University of Wisconsin - Madison
Nasia Safdar, University of Wisconsin - Madison
Lisa Hanson, Marquette UniversityFollow

Document Type

Article

Publication Date

2024

Publisher

Taylor & Francis

Source Publication

Gut Microbes Report

Source ISSN

2993-3935

Original Item ID

DOI: 10.1080/29933935.2024.2334311

Abstract

The gut and vaginal microbiome undergo changes during pregnancy which may be protective or harmful to the birthing person. Probiotics have been found to cause protective changes to the gut and vaginal microbiomes, with the potential to improve perinatal outcomes. This randomized control trial compares the vaginal and rectal microbiomes before and after an antenatal probiotic or placebo intervention, with a diverse group of pregnant people and a special focus on racial disparities. The vaginal and rectal microbiomes reveal non-significant increased Lactobacillus in the probiotics group, with a greater increase in participants who identified as Black. Potential implications and future studies are discussed.

Comments

Gut Microbes Report, Vol. 1, No. 1 (2024). DOI.

Recommended Citation

Malloy, Emily; Kates, Ashley; Dixon, Jonah; Riley, Colleen; Safdar, Nasia; and Hanson, Lisa, "Vaginal and Rectal Microbiome Changes Following Administration of a Multi-Species Antenatal Probiotic: A Randomized Control Trial" (2024). College of Nursing Faculty Research and Publications. 1013.
https://epublications.marquette.edu/nursing_fac/1013