Short Term Regulation of Energy Intake is Intact in Hypophagic Tumor-Bearing Rats
Format of Original
Research in Nursing and Health
Original Item ID
doi: 10.1002/(SICI)1098-240X(199710)20:5<425::AID-NUR6>3.0.CO;2-Q; Shelves: RT1 .R48x Raynor Memorial Periodicals
Anorexia and weight loss are major problems in the care of cancer patients. Data from laboratory studies using an animal model of tumor-induced anorexia suggest that energy intake may be regulated in the tumor-bearing host as it is in healthy animals. The purpose of the pres-ent study was to determine if hypophagic tumor-bearing rats would alter their food intake in response to manipulations known to affect food intake in normal healthy animals. Both tumor-bearing and healthy animals increased their food intake when housed at 22 versus 258° C and reduced their food intake when injected with anorexigenic doses of bacterial lipopolysaccharide or interleukin-1 alpha. These data suggest that selected physiological responses affecting short-term food intake are intact in the hypophagic tumor bearing host. © 1997 John Wiley & Sons, Inc. Res Nurs Health 20: 425–429, 1997
McCarthy, Donna O., "Short Term Regulation of Energy Intake is Intact in Hypophagic Tumor-Bearing Rats" (1997). College of Nursing Faculty Research and Publications. 198.