Document Type




Publication Date



Lippincott Williams & Wilkins

Source Publication

Advances in Skin & Wound Care

Source ISSN



OBJECTIVE: To determine the effect of noncontact normothermic wound therapy (NNWT) versus standard wound care on chronic full-thickness pressure ulcers.

DESIGN: Prospective, randomized, controlled trial

SETTING: Veterans administration medical center and 7 long-term-care facilities

PATIENTS: 40 inpatients with 43 Stage III and IV pressure ulcers

INTERVENTIONS: A sterile noncontact wound dressing was applied to 21 wounds for 24 hours per day, 7 days per week. Each day after the wound was irrigated and the noncontact dressing was changed, a heating element in the dressing was activated for 3 1-hour periods for 12 weeks or until wound closure. Twenty-two control wounds were treated with standard, moisture-retentive dressings 24 hours per day, 7 days per week for 12 weeks or until wound closure.

MAIN OUTCOME MEASURE: Measurement of wound surface area

MAIN RESULTS: Healing rate for the NNWT group was significantly greater than for the control group (0.52 cm2 per week and 0.23 cm2 per week, respectively;PPP <.05).

CONCLUSION: Wounds treated with NNWT healed significantly faster than wounds in the control group. The healing rate was greatest for larger wounds treated with NNWT.


Accepted version. Advances in Skin & Wound Care, Vol. 15, No. 6 (November/December 2002): 270-276. Permalink. © 2002 Lippincott Williams & Wilkins, Inc. Used with permission.

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