Document Type




Format of Original

4 p.

Publication Date

Winter 2016


Lippincott Williams & Wilkins, Inc.

Source Publication

Pediatric Physical Therapy

Source ISSN



Purpose: Pain relief after exercise, exercise-induced hypoalgesia (EIH), is established across the lifespan. Conditioned pain modulation (CPM: pain inhibits pain) may be a mechanism for EIH.

Methods: In 55 adolescents, pressure pain thresholds were measured before and after exercise (deltoid, quadriceps, and nail bed) and during CPM at the nail bed and deltoid test stimulus sites. The relationship between EIH and CPM was explored.

Results: EIH occurred at deltoid and quadriceps; CPM occurred at nail bed and deltoid. CPM and EIH correlated at deltoid; adolescents with greater CPM experienced greater pain relief after exercise. At this site, CPM predicted 5.4% of EIH. Arm lean mass did not add a significant effect. Peak exercise pain did not influence EIH. Adolescents with none, minimal, moderate, or severe peak exercise pain experienced similar EIH.

Conclusions: A potential relationship exists between CPM and EIH in adolescents. Pediatric physical therapists should consider the CPM response when prescribing exercise as a pain management tool.


Accepted version. Pediatric Physical Therapy, Vol. 28, No. 4 (Winter 2016): 470-473. DOI. © 2016 Academy of Pediatric Physical Therapy of the American Physical Therapy Association. Used with permission.