Date of Award
Spring 1956
Document Type
Thesis - Restricted
Degree Name
Master of Science (MS)
Department
Nursing
First Advisor
Quick, Armand J.
Second Advisor
Brown, Kenneth
Third Advisor
Koch, John R.
Abstract
Over the past three years Dr. K. D. Brown of the biochemistry department of this University has been one of a group attempting to develop a method for the clinical diagnosis of the atherosclerotic state. Early in 1955 the work of Dr. Noland of U.S. Veteran's Administration Hospital, Wood, Wisconsin, was called to the attention of this group. His experimental work dealt with the influence of C-3 analogues of cholesterol on cholesterol absorption in insects. His results indicated that certain of these compounds behaved as inhibitors of cholesterol absorption from the gut. In June, 1955, a research project was begun which was designed to assay the effect on mammals of the compounds found to be inhibitory to cholesterol absorption in insects. If successful this would provide a means of controlling the level of circulating cholesterol and possibly the development of atherosclerosis. The preliminary results of these investigations are reported in this thesis.
Recommended Citation
McHale, Joan M., "The Influence of Cholesterol C-3 Analogues on the Progress of Atherosclerosis 1. Cholesteryl Chloride" (1956). Master's Theses (1922-2009) Access restricted to Marquette Campus. 3632.
https://epublications.marquette.edu/theses/3632