Date of Award

Spring 1955

Degree Type

Thesis - Restricted

Degree Name

Master of Science (MS)




This study was undertaken in an attempt to produce peptic ulceration in the dog by a surgically induced excessive vagal stimulation. The production of peptic ulcer by pharmacologic means (histamine, etc.) and transposition procedures (Mann-Williamson dog) are well known and will not be considered. Most of the previous surgical attempts have been done transthoracically with attendant morbidity and mortality. The method under current consideration was an anastomosis between the central end of the phrenic nerve to the peripheral end of the vagus nerve performed in the neck. Byu this means it was hoped that the constant discharge of impulses from the respiratory center would traverse the anastomosis and activate the postganglionic fibers in the wall of the gastroduodenal tract.



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