Date of Award

Fall 2007

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)


Biomedical Engineering

First Advisor

Harris, Gerald F.

Second Advisor

Wang, Mei

Third Advisor

Strifling, Kelly M. B.


Osteogenesis -imperfecta (OI) is a genetic disease that reduces the activity and employment abilities of those it afflicts. It causes numerous fractures and is not extensively studied in humans. This thesis created a femur fracture risk assessment finite element model that is the beginning step of creating patient-specific fracture prediction models for OI. A repeatable methodology for developing such a model was developed. It is the initial step of providing improved quality of life and expanded prescription of activities of daily living and employment limitations for persons with OI.



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