Document Type
Article
Language
eng
Format of Original
8 p.
Publication Date
8-2016
Publisher
Wiley
Source Publication
Journal of Prosthodontics
Source ISSN
1059-941X
Original Item ID
DOI: 10.1111/jopr.12465
Abstract
Clinical advances in the treatment of dentoalveolar defects continue to evolve with the introduction of new innovations in regenerative medicine and tissue bioengineering. Recent developments in tissue engineering are aimed at safely and effectively regenerating a damaged or necrotic area by replenishing its cells and increasing surrounding gene expression. Various techniques have successfully given rise to porous scaffolds being used by clinicians to treat the defect and initiate the repair process. Tissue reconstruction using bioengineered scaffolds is advantageous over traditional autografting, since it prevents the instigation of pain and donor site morbidity while ultimately creating both the environment and machinery needed to induce cell proliferation, migration, and reattachment within the affected area. This review article aims to describe and review the available literature regarding the regenerative capacity of natural polymers used for the treatment of dentoalveolar defects. The repair mechanisms, advantages of protein and polysaccharide derivatives, and the potential of stem cell therapy are discussed.
Recommended Citation
Jazayeri, Hossein E.; Fahmy, Mina D.; Razavi, Mehdi; Stein, Brett E.; Nowman, Aatif; Masri, Radi; and Tayebi, Lobat, "Dental Applications of Natural-Origin Polymers in Hard and Soft Tissue Engineering" (2016). School of Dentistry Faculty Research and Publications. 189.
https://epublications.marquette.edu/dentistry_fac/189
Comments
Accepted version. Journal of Prosthodontics, Vol. 25, No. 6 (August 2016): 510-517. DOI. © 2016 John Wiley & Sons, Inc. Used with permission.