Date of Award
Thesis - Restricted
Master of Science (MS)
An active finite element model to simulate contraction and thickening of left ventricle during systole h8S been developed. The 3 -D finite element method developed here, has been applied to both passive diastolic and active systolic left ventricular deformations. Isotropic material properties have been used. However, the model can incorporate anisotropic behaviour. The left ventrjcle is considered as three-dimensional two layered myocardium with active contraction. The model is rendered passive by assigning a zero coefficient for the activation function. With proper selection of suitable material properties and activation function, their effect on left ventricular deformatjon pattern can be demonstrated. In this analysis, typical 'Normal', ' Tschemic' and 'Aneurysmal' myocardiums are considered and their deformation patterns for both passive diastolic and active sysstolic behaviour are studied. The model is able to show the 'thinning' of the diseased zone while 'thickening' of the normal myocardium: It also shows the paradoxic motion of the severely diseased myocardium during systole and diastole.
Havele, Vivek V., "Finite Element Model of an Active Material to Study Myocardial Contraction Pattern" (1984). Master's Theses (1922-2009) Access restricted to Marquette Campus. 1262.