Date of Award

1986

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)

Department

Biology

First Advisor

Vomachka, Archie J.

Second Advisor

Horseman, Nelson D.

Third Advisor

Piacsek, Bela E.

Abstract

Production of androgen and estradiol were determined in gonads isolated from female and male golden hamsters during the last 2 days of gestation and the first 3 days after parturition. The ability of the gonads to respond to human chorionic gonadotropin (hCG) stimulation with the production of these steroids was also determined. There was an accumulation of androgen produced by the testes on all of the days examined. The testes were also responsive to hCG stimulation at each of the ages observed. They were unable to produce detectable levels of estradiol on any of the days examined. HCG was not able to cause stimulation of estradiol after parturition. The ovaries did not produce detectable androgen or estradiol in vitro on any of the days examined. HCG was ineffective in stimulating production of either of these steroids after parturition.

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