Smartphone Based Optical Spectrometer for Diffusive Reflectance Spectroscopic Measurement of Hemoglobin

Authors

Perry Edwards, Atoptix, Inc.
Chenji Zhang, Pennsylvania State University
Baigang Zhang, Atoptix, Inc.
Xiangqian Hong, Marquette UniversityFollow
Vivek K. Nagarajan, The University of AkronFollow
Bing Yu, Marquette UniversityFollow
Zhiwen Liu, Pennsylvania State University

Document Type

Article

Publication Date

2017

Publisher

Nature Publishing Group

Source Publication

Scientific Reports

Source ISSN

2045-2322

Abstract

We report a miniature, visible to near infrared G-Fresnel spectrometer that contains a complete spectrograph system, including the detection hardware and connects with a smartphone through a microUSB port for operational control. The smartphone spectrometer is able to achieve a resolution of ~5 nm in a wavelength range from 400 nm to 1000 nm. We further developed a diffuse reflectance spectroscopy system using the smartphone spectrometer and demonstrated the capability of hemoglobin measurement. Proof of concept studies of tissue phantoms yielded a mean error of 9.2% on hemoglobin concentration measurement, comparable to that obtained with a commercial benchtop spectrometer. The smartphone G-Fresnel spectrometer and the diffuse reflectance spectroscopy system can potentially enable new point-of-care opportunities, such as cancer screening.

Comments

Published version. Scientific Reports, Vol. 7, No. 12224 (2017). DOI. © 2017 The Authors published by Nature Publishing Group. Used with permission.

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Recommended Citation

Edwards, Perry; Zhang, Chenji; Zhang, Baigang; Hong, Xiangqian; Nagarajan, Vivek K.; Yu, Bing; and Liu, Zhiwen, "Smartphone Based Optical Spectrometer for Diffusive Reflectance Spectroscopic Measurement of Hemoglobin" (2017). Biomedical Engineering Faculty Research and Publications. 641.
https://epublications.marquette.edu/bioengin_fac/641