Synthesis of a protected 2-(3′-carboxycyclopentyl)glycine rac-11, possessing four contiguous chiral carbons, was accomplished in six steps (20% yield) from the hydrocarbon cyclooctatetraene.
Chaudhury, Subhabrata; Lindeman, Sergey; and Donaldson, William, "Generation of molecular complexity from cyclooctatetraene: synthesis of a protected 2-(3′-carboxy-2′-benzoylcyclopentyl)glycine" (2007). Chemistry Faculty Research and Publications. 49.
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