The dihydropyranyl segment common to ambruticin and jerangolid A was prepared in six steps (31.7% yield) from (S)-2-benzyloxypropanal via silyloxydiene cyclocondensation, followed by C-glycosidation, and eventual epimerization at C18.
Lukesh, Julie and Donaldson, William, "A short synthesis of the common dihydropyran segment of the antifungal agents ambruticin and jerangolid A" (2005). Chemistry Faculty Research and Publications. 58.
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