Document Type

Article

Language

eng

Publication Date

12-1988

Publisher

Cognizant Communication Corporation

Source Publication

Anti-Cancer Drug Design

Source ISSN

0266-9536

Abstract

Evidence is presented in support of an electron transfer mechanism for various metal complexes possessing anti-neoplastic properties. Cyclic voltammetry was performed on several metallocenes, bis(acetato)bis(imidazole)Cu(II), and coordination compounds (Cu or Fe) of the anti-tumor agents, bipyridine, phenanthroline, hydroxyurea, diethyldithiocarbamate, and α, α1-bis(8-hydroxyquinolin-7-yl)-4-methoxytoluene. The favorable reduction potentials ranged from +0.5 to -0.5 V. Electrochemical behavior is correlated in some cases with structure and physiological activity. Relevant literature data are discussed.

Comments

Published version. Anti-Cancer Drug Design, Vol. 3, No. 3 (December 1988): 205-216. Publisher link. © Cognizant Communication Corporation 1986.

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