Title

Cycle Mobility in 1,4-Dihydropyridine and its Monoalkyl and Phenyl Derivatives

Document Type

Article

Language

eng

Publication Date

7-1993

Publisher

Springer

Source Publication

Russian Chemical Bulletin

Source ISSN

1066-5285

Abstract

The conformational mobility of the 1,4-dihydropyridine cycle has been studied by the molecular mechanics method. It was shown that the N(1) and C(4) atoms are displaced asymmetrically from the plane of the double bonds. The asymmetry is the result of conjugation between the nitrogen lone pair and the π systems of the double bonds. The influence of alkyl and phenyl substituents at the carbon atoms on the equilibrium conformation and cycle mobility has been investigated.

Comments

Russian Chemical Bulletin, Vol. 42, No. 7 (July 1993): 1060-1162. DOI.

Sergey Lindeman was affiliated with Russian Academy of Sciences at the time of publication.

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