Regio- and Stereoselective Ruthenium Catalyzed Hydrovinylation of 1,3-Dienes: Application to the Generation of a 20S-Steroidal Sidechain

Authors

Zhengjie He, Marquette UniversityFollow
Chae S. Yi, Marquette UniversityFollow
William A. Donaldson, Marquette UniversityFollow

Document Type

Article

Language

eng

Publication Date

4-2003

Publisher

American Chemical Society

Source Publication

Organic Letters

Source ISSN

1523-7060

Abstract

The addition of ethylene to 1,3-dienes and 1-vinylcycloalkenes, catalyzed by two ruthenium complexes, proceeds in a regioselective fashion to afford 3-methyl-1,4-dienes as products. For a steroidal-based 1-vinylcycloalkene, the addition is stereospecific, giving a product with a 20(S) configuration.

Comments

Accepted version. Organic Letters, Volume 5, No. 9 (2003): 1567-1569. DOI. © 2003 American Chemical Society. Used with permission.

Recommended Citation

He, Zhengjie; Yi, Chae S.; and Donaldson, William A., "Regio- and Stereoselective Ruthenium Catalyzed Hydrovinylation of 1,3-Dienes: Application to the Generation of a 20S-Steroidal Sidechain" (2003). Chemistry Faculty Research and Publications. 80.
https://epublications.marquette.edu/chem_fac/80