Title

Studies on the Preparation of Protomycinolide IV: Enantioselective Synthesis of the C3–C9 Segment

Document Type

Article

Language

eng

Publication Date

1-16-1998

Publisher

Elsevier

Source Publication

Tetrahedron: Asymmetry

Source ISSN

0957-4166

Abstract

The C3–C9 segment, (−)-16, of the polyene macrolide antibiotic protomycinolide IV (1a) was prepared in optically pure form from commercially available methyl (S)-2-methyl-3-hydroxypropionate in 12 steps giving 17% yield.

Comments

Tetrahedron: Asymmetry, Vol. 9, No. 1 (January 16. 1998): 133-140. DOI.

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