Title

Histologic and Histomorphometric Analysis of Posterior Region of the Human Temporomandibular Disc

Document Type

Article

Language

eng

Publication Date

4-2008

Publisher

Elsevier

Source Publication

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Source ISSN

2212-4403

Abstract

Objective

The aim of this study was to analyze histologic and histomorphometric features of the articular disc in groups with and without disc displacement.

Study design

A sample of 39 temporomandibular joints TMJs (31 case specimens, 8 control specimens) from 28 patients (mean age 31.2 years) were recruited for this study. The patients were considered to be affected and treated surgically with disc repositioning when presenting painful clinical signs of disc displacement after unsuccessful nonsurgical treatment for at least 6 months. Of the control patients, 4 presented condyle fracture which required opening to be reduced for treatment, and 4 displayed active condyle hyperplasia. The posterior region of the disc was removed and sent for histologic and histomorphometric analysis. Histologic (hematoxylin-eosin) and histomorphometric (picro-Sirius red) analyses were performed. Statistically significant differences between the analyzed groups were accessed through the chi-squared test (P ≤ .05). The Mann-Whitney U test was used to observe the differences between mean values when variables did not present normal distribution [Kolmogorov-Smirnov(a) test].

Results

There were no significant differences between the groups in relation to the parameters studied by histologic and histomorphometric analysis (using or not using polarization).

Conclusions

To the limits of this study, there were no significant histologic and histomorphometric differences in the articular disc between groups with and without TMJ dysfunction.

Comments

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, Vol. 105, No. 4 (April 2008): e6-e11. DOI

Luis Eduardo Almeida was affiliated with Department of Oral and Maxillofacial Surgery, Hospital Evalgelico e Curitiba, Curitiba, Brazil at the time of publication.

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