Conserved Cysteines in the Vitelline Membrane Domain of the Drosophila sV23 Eggshell Protein are Functionally Distinct
Date of Award
Dissertation - Restricted
Doctor of Philosophy (PhD)
Cells in most multicellular organisms are surrounded by a complex network of mixed molecules, the extracellular matrix (ECM). Assembled in complicated environments, extracellular matrix networks provide numerous functions, the most obvious being mechanical support and a substrate for anchoring cells and organs. More importantly, extracellular matrice host secreted molecules regulating cell differentiation, tissue remodeling, and morphology. To perform these structural and regulatory functions, the ECM has to be properly assembled...