Date of Award

Spring 2015

Document Type


Degree Name

Doctor of Philosophy (PhD)


Mathematics, Statistics and Computer Science


Computational Sciences

First Advisor

Ahamed, Sheikh I.

Second Advisor

Amy Vaughan Van Hecke

Third Advisor

Bozdag, Serdar


The prevalence rate of Autism Spectrum Disorders (ASD) is increasing at an alarming rate (1 in 68 children). With this increase comes the need of early diagnosis of ASD, timely intervention, and understanding the conditions that could be comorbid to ASD. Understanding co-morbid anxiety and its interaction with emotion comprehension and production in ASD is a growing and multifaceted area of research. Recognizing and producing contingent emotional expressions is a complex task, which is even more difficult for individuals with ASD. First, I investigate the arousal experienced by adolescents with ASD in a group therapy setting. In this study I identify the instances in which the physiological arousal is experienced by adolescents with ASD ("have-it"), see if the facial expressions of these adolescents indicate their arousal ("show-it"), and determine if the adolescents are self-aware of this arousal or not ("know-it"). In order to establish a relationship across these three components of emotion expression and recognition, a multi-modal approach for data collection is utilized. Machine learning techniques are used to determine whether still video images of facial expressions could be used to predict Electrodermal Activity (EDA) data. Implications for the understanding of emotion and social communication difficulties in ASD, as well as future targets for intervention, are discussed. Second, it is hypothesized that a well-designed intervention technique helps in the overall development of children with ASD by improving their level of functioning. I designed and validated a mobile-based intervention designed for teaching social skills to children with ASD. I also evaluated the social skill intervention. Last, I present the research goals behind an mHealth-based screening tool for early diagnosis of ASD in toddlers. The design purpose of this tool is to help people from low-income group, who have limited access to resources. This goal is achieved without burdening the physicians, their staff, and the insurance companies.