Document Type




Format of Original

6 p.

Publication Date



Elsevier Inc.

Source Publication

Intensive and Critical Care Nursing

Source ISSN


Original Item ID

DOI: 1016/j.iccn.2016.01.003, PubMed Central: PMC26916664


Objective: Sleep disruption occurs frequently in critically ill patients. The primary aim of this study was to examine the effect of quiet time (QT) on patient sedation frequency, sedation and delirium scores; and to determine if consecutive QTs influenced physiologic measures (heart rate, mean arterial blood pressure and respiratory rate).

Method: A prospective study of a quiet time protocol was conducted with 72 adult patients on mechanical ventilation.

Setting: A Medical Intensive Care Unit (MICU) in the Midwest region of the United States.

Results: Sedation was given less frequently after QT (p = 0.045). Those who were agitated prior to QT were more likely to be at goal sedation after QT (p < 0.001). Although not statistically significant, the majority of patients who were negative on the Confusion Assessment Method (CAM-ICU) prior to QT remained delirium free after QT. Repeated measures analysis of variance (ANOVA) for three consecutive QTs showed a significant difference for respiratory rate (p = 0.035).

Conclusion: QT may influence sedation administration and promote patient rest. Future studies are required to further understand the influence of QT on mechanically ventilated patients in the intensive care unit.


Accepted version. Intensive and Critical Care Nursing, Vol. 35 (August 2016): 22-27. Publisher Link. © 2016 Elsevier Ltd. Used with permission.

NOTICE: this is the author’s version of a work that was accepted for publication in Intensive and Critical Care Nursing. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Intensive and Critical Care Nursing, Vol. 35 (August 2016): 22-27. DOI.

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