Using the Consolidated Framework for Implementation Research to Evaluate Clinical Trials: An Example from Multisite Nursing Research
The Consolidated Framework for Implementation Research (CFIR) is a comprehensive guide for determining the factors that affect successful implementation of complex interventions embedded in real-time clinical practice.
The study aim was to understand implementation constructs in a multi-site translational research study on readiness for hospital discharge that distinguished study sites with low versus high implementation fidelity.
In this descriptive study, site Principal Investigator interviews (from 8 highest and 8 lowest fidelity sites) were framed with questions from 20 relevant CFIR constructs. Analysis used CFIR rules and rating scale (+2 to −2 per site) and memos created in NVivo 11.
From a bimodal distribution of differences (1.5 and 5), 7 constructs distinguished high and low fidelity sites with ≥5-point difference.
CFIR provided a determinant framework for identifying elements of a study site's context that impact implementation fidelity and clinical research outcomes.
Costa, Linda L.; Bobay, Kathleen L.; Hughes, Ronda G.; Bahr, Sarah J.; Siclovan, Danielle M.; Nuccio, Susan A.; and Weiss, Marianne E., "Using the Consolidated Framework for Implementation Research to Evaluate Clinical Trials: An Example from Multisite Nursing Research" (2020). College of Nursing Faculty Research and Publications. 812.
ADA Accessible Version
Accepted version. Nursing Outlook, Vol. 68, No. 6 (November-December 2020): 769-783. DOI. © 2020 Elsevier. Used with permission.