Date of Award

Summer 1953

Degree Type

Thesis - Restricted

Degree Name

Master of Science (MS)



First Advisor

Haymaker, Clifford R.

Second Advisor

Koch, John R.

Third Advisor

Toralballa, Gloria


In the fields of biochemistry and organic chemistry, the synthesis of fatty acids has occupied the attention of countless investigators for over a century. However, the present day organic chemist, because of his specialized equipment and varied techniques, has not only been able to reproduce the naturally occurring fatty acids, that is, those produced by plants and animals, but has also been able to synthesize acids which have had no previous existence in nature. One of the beat and most practical methods for the synthesis of these fatty acids at the disposal of the modern organic chemist is the preparation employing malonic ester. The method can be used equally wall for the synthesis of long or short chain fatty acids. The author, through the mechanism of this preparation, has attempted the synthesis of various isomers of stearic acid. In hopes of preparing stearic acid isomers containing chains with multiple branching, the author also attempted the synthesis of secondary and tertiary substituted malonic esters.



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