Date of Award

Spring 1951

Degree Type

Thesis - Restricted

Degree Name

Master of Science (MS)




The adult Chinese liver fluke, Clonorchis sinensis (Cobbold), is occupied chiefly in propagation. The average daily egg-laying capacity per fluke in a cat as the host is 2400 eggs (Faust and Khaw '26). Egg laying is continuous rather than cyclic. Since these flukes have a size range from 10 to 25 mm. in length by 3 to 5 mm. in breadth (Faust '49), the reproductive system involved in such enormous egg production is necessarily intricate. A study of whole mounts fails to answer many morphological questions which arise. There is no published account ot the histology of clonorchis sinensis. Although the student can refer to any reliable textbook for a picture of the gross anatomy, he is bewildered when he compares such a picture to the whole-mount fluke on his slide. Questions invariably arise as to how the presence and position of a structure such as Mehlis' gland and the fate of Laurer's canal were determined by the writer. It is hoped that, through this investigation into the history of our knowledge of this fluke and also through the histological analysis, its true morphological condition will be ascertained in reference to the reproductive mechanism. "When we attempt to discuss any subject having a direct relation to the welfare of our species, it is of the utmost importance that we seed to discriminate the true and the false, stating no more than our facts will fairly allow, and theorizing as little as possible; for although the diffusion of scientific information cannot but be fraught with the happiest results 'in the long run', yet meanwhile, the most serious harm may accrue if our leaders of public opinion permit themselves to be misled by the too ardent assurances of imperfectly informed individuals. To effect any real and permanent good, it is absolutely essential that our writers be animated with an entire singleness of purpose, that their statement be made with the modesty that distinguishes the true savant, and that they themselves be more or less practically acquainted with the subject they propose to open up. In this attitude it is my desire to offer the following observations:--"