Date of Award

Fall 1950

Degree Type

Thesis - Restricted

Degree Name

Master of Science (MS)




Since both complement and prothrombin are composed of a number of components which are constituents of blood plasma, and since several of these components exhibit rather striking similarities in their physical characteristics; various attempts have been made to demonstrate a relationship between them. However, technical difficulties have, in the past, prevented workers from obtaining conclusive results. Methods, recently developed in our laboratory, now make it possible to separate the prothrombin complex into its constituent parts, thus enabling a much more detailed study of this particular problem. It has been the purpose of this research to apply these newly developed methods in a manner suitable for demonstrating a relationship between the components of complement and the various constituents of the prothrombin complex.



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