Date of Award

Summer 1963

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)



First Advisor

Boucher, Louis

Second Advisor

Gehl, Daniel

Third Advisor

Ryge, Gunnar


For centuries the dental profession has been in search of an ideal denture base material, and a great deal of the research has been done to develop such a material. The first and foremost requirement of a denture base material is that it should be well tolerated by the oral tissues. How does the oral mucosa react toward different denture base materials? What is the histologic appearance of the oral epithelium under different denture base materials? Is the denture base material responsible for denture irritation? These are some of the questions which arise in the minds of the dentists. The need to solve some of these problems motivated this study. The purpose of this study has been two fold: 1. To evaluate the histologic response of the oral mucosa to different denture base materials under the same environment. 2. To devise a procedure by which further histologic studies can be made on animals using various denture base materials. This study is confined to evaluate the response of the Stratum Corneum, the most superficial layer of the oral mucosa, to different denture base materials. The denture base materials employed in this study were, Acrylic Resin and Vulcanite. Adult domestic cats were used, as experimental animals, to carry out this study.



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