Date of Award

Spring 2008

Document Type

Thesis - Restricted

Degree Name

Master of Science (MS)



First Advisor

Toth, Jeffrey M.

Second Advisor

Hodgson, Brian D.

Third Advisor

Bradley, T. G.


Demineralized ''white spot" enamel lesions contributing to unaesthetic treatment results may be present prior to orthodontic treatment or occur during orthodontic treatment due to poor oral hygiene and the accumulation of bacterial plaque on the enamel surfaces adjacent to fixed appliances. The purpose of this study was to assess the efficacy of CPP-ACP paste in the remineralization of artificially demineralized enamel white spot lesions. Forty-five human molars were sectioned into 4 and randomly divided into 3 groups (3 week, 6 week, 9 week) and 4 subgroups: (1) No paste; (2) Recaldent paste without CPP-ACP; (3) Recaldent paste with CPP-ACP; (4) Recaldent paste with CPP-ACP with Fluoride The samples were artificially demineralized and were then stored in artificial saliva. The appropriate paste was applied to the teeth of groups 2, 3 and 4 two times/day for 5 minutes, 5 days/week and group I served as the control. A Faxitron microradiograph unit and a Leica DFC 280 digital camera were used at weeks 3, 6, and 9 to determine the enamel mineral density. Subsurface microscopic lesions were not created with Linton's demineralization solution formula, but rather erosive-like lesions. CPP-ACP paste does not create new layers of enamel, therefore additional studies must be conducted to test Recaldent's rernineralization capability on white spot lesions. This study was supported by GC America Inc.



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