Date of Award

Spring 2011

Document Type


Degree Name

Master of Science (MS)



First Advisor

Bahcall, James K.

Second Advisor

Olsen, Kris F.

Third Advisor

Berzins, David W.


INTRODUCTION: The purpose of this in vitro study was to compare the push-out bond strengths of three endodontic sealers with and without amoxicillin. METHODS: Thirty single-rooted extracted human teeth were used for this study. Each tooth was instrumented and irrigated with 5.25% NaOCl and 17% EDTA. The teeth were then divided into six test groups. Group 1-gutta percha (GP)/AH Plus®, group 1a-GP/AH Plus® with 10% by weight amoxicillin, group 2-GP/Pulp canal sealer EWTTM, group 2a-GP/Pulp canal sealer EWTTM with amoxicillin, group 3-Resilon® /RealSeal SETM, and group 3a-Resilon® /RealSeal SETM with amoxicillin. After the sealer was set the entire root was sectioned into 1mm thick slices. A push-out bond strength test was preformed using a universal testing machine. The Mann Whiney and Student's t-test were used to compare the sealer bond strength within the specific sealer test groups overall and within each sealer at apical, middle and coronal root levels. The film thickness, dimensional change and the solubility of each sealer were also tested according to ISO standards. RESULTS: There was no significant difference between test groups within each sealer, Group 1 vs. Group 1a (p=.85), Group 2 vs. Group 2a (p=.59) or Group 3 vs. Group 3a (p=.52). There was no significant difference (p>.05) in push-out bond strength within each sealer with or without amoxicillin at the same root level. Significant differences were seen in film thickness and dimensional change when amoxicillin was added to the sealers. CONCLUSION: The addition of 10% by weight of amoxicillin does not significantly (p>.05) change the overall push-out bond strength of GP/AH Plus®, GP/Pulp canal sealer EWTTM and Resilon® /RealSeal SETM or when compared at the apical, middle and coronal tooth level.