Nucleosome Positioning Is Independent of Histone H1 in Vivo

Document Type

Article

Language

eng

Format of Original

5 p.

Publication Date

11-12-1999

Publisher

American Society for Biochemistry and Molecular Biology

Source Publication

Journal of Biological Chemistry

Source ISSN

0021-9258

Abstract

Nucleosome positioning in the somatic macronuclear genome of the ciliated protozoan Tetrahymena thermophila was analyzed by indirect end labeling. Nucleosomes were positioned nonrandomly in three different regions of theTetrahymena genome. Nucleosome repeat length varied between adjacent nucleosomes. Nucleosome positioning in a histone H1 knockout strain was indistinguishable from that in a strain with wild type histone H1.

Comments

Journal of Biological Chemistry, Vol. 274, No. 46 (November 12, 1999): 33020-33024. DOI.

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